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KMID : 1189320210150060874
Asian Spine Journal
2021 Volume.15 No. 6 p.874 ~ p.880
Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country
Sharma Vyom

Jafri Haris
Roy Nilanjan
Dangi Manish
Kataruka Mohit
Abstract
Respiratory failure and chronic ventilator dependence in tetraplegics following cervical injuries located high on the spine (C1?C3) constitute significant challenges in the rehabilitation of patients given the occurrence of repeated hospitalizations and an ever-increasing financial burden. A 30-year-old man presented with posttraumatic tetraplegia following an unstable injury at the C1?C2 level with cord compression; he was managed by posterior stabilization and decompression followed by ventilator dependence and no rehabilitation until 6 months postinjury. We implanted phrenic nerve stimulator electrodes bilaterally for indirect diaphragm pacing by an implantable pulse generator that allowed for weaning from mechanical ventilation and spontaneous ventilator-free breathing at 20 weeks post-implantation and which facilitated post-tetraplegia rehabilitation. At 36 months after implantation, the patient is ventilator-free without any procedure-related complications or respiratory infections. Diaphragm pacing with phrenic nerve stimulation may be a way forward for ventilator-dependent tetraplegics in developing countries to pursue effective rehabilitation and improved quality of life.
KEYWORD
Phrenic nerve stimulation with diaphragm pacing, Traumatic tetraplegia, Ventilator dependence, Spinal cord injury rehabilitation
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